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Protecting Encapsulin Nanoparticles with Cysteine-Knot Miniproteins
[Image: see text] A big hurdle for the use of protein-based drugs is that they are easily degraded by proteases in the human body. In an attempt to solve this problem, we show the possibility to functionalize TM encapsulin nanoparticles with an mEETI-II knottin miniprotein from the cysteine-stabiliz...
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| Publié dans: | Mol Pharm |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Chemical
Society
2018
|
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6143317/ https://ncbi.nlm.nih.gov/pubmed/30047270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.8b00630 |
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