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The C-terminus of varicella-zoster virus glycoprotein M contains trafficking motifs that mediate skin virulence in the SCID-human model of VZV pathogenesis

Knowledge about the function of varicella-zoster virus glycoprotein M is limited; the requirement of gM for skin and neural tropism are unknown. VZV gM contains two predicted YXXΦ trafficking motifs and a dileucine motif in the carboxyl-terminus. We constructed a recombinant VZV with gM truncated fr...

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Bibliografski detalji
Izdano u:Virology
Glavni autori: Leigh, Zerboni, Phillip, Sung, Marvin, Sommer, Ann, Arvin
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143146/
https://ncbi.nlm.nih.gov/pubmed/30119012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2018.08.003
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