Interactive Associations of Vascular Risk and β-Amyloid Burden With Cognitive Decline in Clinically Normal Elderly Individuals: Findings From the Harvard Aging Brain Study

IMPORTANCE: Identifying asymptomatic individuals at high risk of impending cognitive decline because of Alzheimer disease is crucial for successful prevention of dementia. Vascular risk and β-amyloid (Aβ) pathology commonly co-occur in older adults and are significant causes of cognitive impairment....

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Udgivet i:JAMA Neurol
Main Authors: Rabin, Jennifer S., Schultz, Aaron P., Hedden, Trey, Viswanathan, Anand, Marshall, Gad A., Kilpatrick, Emily, Klein, Hannah, Buckley, Rachel F., Yang, Hyun-Sik, Properzi, Michael, Rao, Vaishnavi, Kirn, Dylan R., Papp, Kathryn V., Rentz, Dorene M., Johnson, Keith A., Sperling, Reisa A., Chhatwal, Jasmeer P.
Format: Artigo
Sprog:Inglês
Udgivet: American Medical Association 2018
Fag:
Original Investigation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143121/
https://ncbi.nlm.nih.gov/pubmed/29799986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2018.1123
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