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Mutational landscape of a chemically-induced mouse model of liver cancer

BACKGROUND & AIMS: Carcinogen-induced mouse models of liver cancer are used extensively to study the pathogenesis of the disease and are critical for validating candidate therapeutics. These models can recapitulate molecular and histological features of human disease. However, it is not known if...

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Detalhes bibliográficos
Publicado no:J Hepatol
Main Authors: Connor, Frances, Rayner, Tim F., Aitken, Sarah J., Feig, Christine, Lukk, Margus, Santoyo-Lopez, Javier, Odom, Duncan T.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142872/
https://ncbi.nlm.nih.gov/pubmed/29958939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2018.06.009
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