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Mutational landscape of a chemically-induced mouse model of liver cancer

BACKGROUND & AIMS: Carcinogen-induced mouse models of liver cancer are used extensively to study the pathogenesis of the disease and are critical for validating candidate therapeutics. These models can recapitulate molecular and histological features of human disease. However, it is not known if...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Hepatol
Hauptverfasser: Connor, Frances, Rayner, Tim F., Aitken, Sarah J., Feig, Christine, Lukk, Margus, Santoyo-Lopez, Javier, Odom, Duncan T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142872/
https://ncbi.nlm.nih.gov/pubmed/29958939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2018.06.009
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