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Biophysical analysis of sialic acid recognition by the complement regulator Factor H
Complement factor H (FH), an elongated and substantially glycosylated 20-domain protein, is a soluble regulator of the complement alternative pathway (AP). It contains several glycan binding sites which mediate recognition of α2-3-linked sialic acid (FH domain 20) and glycosaminoglycans (domains 6–8...
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| Publicado no: | Glycobiology |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6142864/ https://ncbi.nlm.nih.gov/pubmed/29982679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwy061 |
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