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Cardiovascular complications in patients with sickle cell disease

Sickle cell disease (SCD) is an autosomal recessive disease in which homozygosity for a single point mutation in the gene encoding the β-globin chain produces hemoglobin S molecules that polymerize within the erythrocyte during deoxygenation; the result is sustained hemolytic anemia and vaso-occlusi...

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Publicat a:Hematology Am Soc Hematol Educ Program
Autor principal: Gladwin, Mark T.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142571/
https://ncbi.nlm.nih.gov/pubmed/29222288
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