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CD6 monoclonal antibodies differ in epitope, kinetics and mechanism of action
CD6 is a type I T‐cell surface receptor that modulates antigen receptor signalling. Its activity is regulated by binding of its membrane proximal domain (domain 3) to a cell surface ligand, CD166. CD6 monoclonal antibodies (mAbs) specific for the membrane distal domain (domain 1) perturb CD6 functio...
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| Gepubliceerd in: | Immunology |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
John Wiley and Sons Inc.
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6142284/ https://ncbi.nlm.nih.gov/pubmed/29772075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12952 |
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