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Indel-correcting DNA barcodes for high-throughput sequencing

Many large-scale, high-throughput experiments use DNA barcodes, short DNA sequences prepended to DNA libraries, for identification of individuals in pooled biomolecule populations. However, DNA synthesis and sequencing errors confound the correct interpretation of observed barcodes and can lead to s...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Hawkins, John A., Jones, Stephen K., Finkelstein, Ilya J., Press, William H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142223/
https://ncbi.nlm.nih.gov/pubmed/29925596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802640115
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