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Denoising DNA deep sequencing data—high-throughput sequencing errors and their correction

Characterizing the errors generated by common high-throughput sequencing platforms and telling true genetic variation from technical artefacts are two interdependent steps, essential to many analyses such as single nucleotide variant calling, haplotype inference, sequence assembly and evolutionary s...

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Библиографические подробности
Опубликовано в: :Brief Bioinform
Главные авторы: Laehnemann, David, Borkhardt, Arndt, McHardy, Alice Carolyn
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719071/
https://ncbi.nlm.nih.gov/pubmed/26026159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbv029
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