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Denoising DNA deep sequencing data—high-throughput sequencing errors and their correction

Characterizing the errors generated by common high-throughput sequencing platforms and telling true genetic variation from technical artefacts are two interdependent steps, essential to many analyses such as single nucleotide variant calling, haplotype inference, sequence assembly and evolutionary s...

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Detalhes bibliográficos
Publicado no:Brief Bioinform
Main Authors: Laehnemann, David, Borkhardt, Arndt, McHardy, Alice Carolyn
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719071/
https://ncbi.nlm.nih.gov/pubmed/26026159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbv029
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