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High Throughput Sequencing Revolution Reveals Conserved Fundamentals of U-indel Editing

Among Euglenozoans, mitochondrial RNA editing occurs in the diplonemids and in the kinetoplastids that include parasitic trypanosomes. Yet U-indel editing, in which open reading frames (ORFs) on mRNAs are generated by insertion and deletion of uridylates in locations dictated by guide RNAs, appears...

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Vydáno v:Wiley Interdiscip Rev RNA
Hlavní autoři: Zimmer, Sara L., Simpson, Rachel M., Read, Laurie K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289883/
https://ncbi.nlm.nih.gov/pubmed/29888550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.1487
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