Deficient LRRC8A-dependent volume-regulated anion channel activity is associated with male infertility in mice

Ion channel-controlled cell volume regulation is of fundamental significance to the physiological function of sperm. In addition to volume regulation, LRRC8A-dependent volume-regulated anion channel (VRAC) activity is involved in cell cycle progression, insulin signaling, and cisplatin resistance. N...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Bao, Jianqiang, Perez, Carlos J., Kim, Jeesun, Zhang, Huan, Murphy, Caitlin J., Hamidi, Tewfik, Jaubert, Jean, Platt, Craig D., Chou, Janet, Deng, Meichun, Zhou, Meng-Hua, Huang, Yuying, Gaitán-Peñas, Héctor, Guénet, Jean-Louis, Lin, Kevin, Lu, Yue, Chen, Taiping, Bedford, Mark T., Dent, Sharon Y.R., Richburg, John H., Estévez, Raúl, Pan, Hui-Lin, Geha, Raif S., Shi, Qinghua, Benavides, Fernando
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141173/
https://ncbi.nlm.nih.gov/pubmed/30135305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99767
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