Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody

The P2X7 channel is involved in the pathogenesis of various CNS diseases. An increasing number of studies suggest its presence in neurons where its putative functions remain controversial for more than a decade. To resolve this issue and to provide a model for analysis of P2X7 functions, we generate...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Kaczmarek-Hajek, Karina, Zhang, Jiong, Kopp, Robin, Grosche, Antje, Rissiek, Björn, Saul, Anika, Bruzzone, Santina, Engel, Tobias, Jooss, Tina, Krautloher, Anna, Schuster, Stefanie, Magnus, Tim, Stadelmann, Christine, Sirko, Swetlana, Koch-Nolte, Friedrich, Eulenburg, Volker, Nicke, Annette
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Immunology and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6140716/
https://ncbi.nlm.nih.gov/pubmed/30074479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.36217
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