Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody

The P2X7 channel is involved in the pathogenesis of various CNS diseases. An increasing number of studies suggest its presence in neurons where its putative functions remain controversial for more than a decade. To resolve this issue and to provide a model for analysis of P2X7 functions, we generate...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Kaczmarek-Hajek, Karina, Zhang, Jiong, Kopp, Robin, Grosche, Antje, Rissiek, Björn, Saul, Anika, Bruzzone, Santina, Engel, Tobias, Jooss, Tina, Krautloher, Anna, Schuster, Stefanie, Magnus, Tim, Stadelmann, Christine, Sirko, Swetlana, Koch-Nolte, Friedrich, Eulenburg, Volker, Nicke, Annette
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2018
Gaiak:
Immunology and Inflammation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6140716/
https://ncbi.nlm.nih.gov/pubmed/30074479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.36217
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