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Size and topology modulate the effects of frustration in protein folding

The presence of conflicting interactions, or frustration, determines how fast biomolecules can explore their configurational landscapes. Recent experiments have provided cases of systems with slow reconfiguration dynamics, perhaps arising from frustration. While it is well known that protein folding...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kluber, Alex, Burt, Timothy A., Clementi, Cecilia
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6140544/
https://ncbi.nlm.nih.gov/pubmed/30150375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801406115
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