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Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology

Phosphorylation of myristoylated alanine-rich C kinase substrate (MARCKS) reflects neurite degeneration at the early stage of Alzheimer’s disease (AD), before extracellular Aβ aggregates are histologically detectable. Here, we demonstrate that similar changes in MARCKS occur in Parkinson’s disease (...

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Dettagli Bibliografici
Pubblicato in:eNeuro
Autori principali: Fujita, Kyota, Homma, Hidenori, Kondo, Kanoh, Ikuno, Masashi, Yamakado, Hodaka, Tagawa, Kazuhiko, Murayama, Shigeo, Takahashi, Ryosuke, Okazawa, Hitoshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6140116/
https://ncbi.nlm.nih.gov/pubmed/30225354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0217-18.2018
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