HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer’s disease

Alzheimer’s disease (AD) is the most common neurodegenerative disease, but it remains an intractable condition. Its pathogenesis is predominantly attributed to the aggregation and transmission of two molecules, Aβ and tau; however, other pathological mechanisms are possible. Here, we reveal that pho...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Fujita, Kyota, Motoki, Kazumi, Tagawa, Kazuhiko, Chen, Xigui, Hama, Hiroshi, Nakajima, Kazuyuki, Homma, Hidenori, Tamura, Takuya, Watanabe, Hirohisa, Katsuno, Masahisa, Matsumi, Chiemi, Kajikawa, Masunori, Saito, Takashi, Saido, Takaomi, Sobue, Gen, Miyawaki, Atsushi, Okazawa, Hitoshi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997258/
https://ncbi.nlm.nih.gov/pubmed/27557632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31895
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