Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology

Phosphorylation of myristoylated alanine-rich C kinase substrate (MARCKS) reflects neurite degeneration at the early stage of Alzheimer’s disease (AD), before extracellular Aβ aggregates are histologically detectable. Here, we demonstrate that similar changes in MARCKS occur in Parkinson’s disease (...

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Detalhes bibliográficos
Publicado no:eNeuro
Main Authors: Fujita, Kyota, Homma, Hidenori, Kondo, Kanoh, Ikuno, Masashi, Yamakado, Hodaka, Tagawa, Kazuhiko, Murayama, Shigeo, Takahashi, Ryosuke, Okazawa, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
New Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6140116/
https://ncbi.nlm.nih.gov/pubmed/30225354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0217-18.2018
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