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Structure–function analyses reveal the mechanism of the ARH3-dependent hydrolysis of ADP-ribosylation

ADP-ribosylation of proteins plays key roles in multiple biological processes, including DNA damage repair. Recent evidence suggests that serine is an important acceptor for ADP-ribosylation, and that serine ADP-ribosylation is hydrolyzed by ADP-ribosylhydrolase 3 (ARH3 or ADPRHL2). However, the str...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Wang, Mengxi, Yuan, Zenglin, Xie, Rong, Ma, Yinliang, Liu, Xiuhua, Yu, Xiaochun
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139573/
https://ncbi.nlm.nih.gov/pubmed/30045870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004284
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