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AI26 inhibits the ADP-ribosylhydrolase ARH3 and suppresses DNA damage repair
The ADP-ribosylhydrolase ARH3 plays a key role in DNA damage repair, digesting poly(ADP-ribose) and removing ADP-ribose from serine residues of the substrates. Specific inhibitors that selectively target ARH3 would be a useful tool to examine DNA damage repair, as well as a possible strategy for tum...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7535916/ https://ncbi.nlm.nih.gov/pubmed/32753484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012801 |
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