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Cue-Polarized Transport of β-actin mRNA Depends on 3′UTR and Microtubules in Live Growth Cones

Guidance cues trigger fast responses in axonal growth cones such as directional turning and collapse that require local protein synthesis. An attractive cue-gradient, such as Netrin-1, triggers de novo synthesis of β-actin localized to the near-side compartment of the growth cone that promotes F-act...

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Bibliografski detalji
Izdano u:Front Cell Neurosci
Glavni autori: Leung, Kin-Mei, Lu, Bo, Wong, Hovy Ho-Wai, Lin, Julie Qiaojin, Turner-Bridger, Benita, Holt, Christine E.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139529/
https://ncbi.nlm.nih.gov/pubmed/30250426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00300
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