Cue-Polarized Transport of β-actin mRNA Depends on 3′UTR and Microtubules in Live Growth Cones

Guidance cues trigger fast responses in axonal growth cones such as directional turning and collapse that require local protein synthesis. An attractive cue-gradient, such as Netrin-1, triggers de novo synthesis of β-actin localized to the near-side compartment of the growth cone that promotes F-act...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Cell Neurosci
Egile Nagusiak: Leung, Kin-Mei, Lu, Bo, Wong, Hovy Ho-Wai, Lin, Julie Qiaojin, Turner-Bridger, Benita, Holt, Christine E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2018
Gaiak:
Neuroscience
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139529/
https://ncbi.nlm.nih.gov/pubmed/30250426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00300
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