Organic anion transporter OAT3 enhances the glucosuric effect of the SGLT2 inhibitor empagliflozin

The sodium-glucose cotransporter SGLT2 inhibitor empagliflozin (plasma protein binding ~88%) may reach its target in the brush border of the early proximal tubule by glomerular filtration and tubular secretion. Here we determined whether empagliflozin is secreted by renal tubules in mice and whether...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Am J Physiol Renal Physiol
मुख्य लेखकों: Fu, Yiling, Breljak, Davorka, Onishi, Akira, Batz, Falk, Patel, Rohit, Huang, Winnie, Song, Panai, Freeman, Brent, Mayoux, Eric, Koepsell, Hermann, Anzai, Naohiko, Nigam, Sanjay K., Sabolic, Ivan, Vallon, Volker
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Physiological Society 2018
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139528/
https://ncbi.nlm.nih.gov/pubmed/29412698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00503.2017
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन