Iron and Alzheimer’s Disease: From Pathogenesis to Therapeutic Implications

As people age, iron deposits in different areas of the brain may impair normal cognitive function and behavior. Abnormal iron metabolism generates hydroxyl radicals through the Fenton reaction, triggers oxidative stress reactions, damages cell lipids, protein and DNA structure and function, and ulti...

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Опубликовано в: :Front Neurosci
Главные авторы: Liu, Jun-Lin, Fan, Yong-Gang, Yang, Zheng-Sheng, Wang, Zhan-You, Guo, Chuang
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2018
Предметы:
Neuroscience
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139360/
https://ncbi.nlm.nih.gov/pubmed/30250423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00632
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