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Iron and Alzheimer’s Disease: From Pathogenesis to Therapeutic Implications
As people age, iron deposits in different areas of the brain may impair normal cognitive function and behavior. Abnormal iron metabolism generates hydroxyl radicals through the Fenton reaction, triggers oxidative stress reactions, damages cell lipids, protein and DNA structure and function, and ulti...
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| Pubblicato in: | Front Neurosci |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6139360/ https://ncbi.nlm.nih.gov/pubmed/30250423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00632 |
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