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Iron and Alzheimer’s Disease: From Pathogenesis to Therapeutic Implications

As people age, iron deposits in different areas of the brain may impair normal cognitive function and behavior. Abnormal iron metabolism generates hydroxyl radicals through the Fenton reaction, triggers oxidative stress reactions, damages cell lipids, protein and DNA structure and function, and ulti...

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Bibliografske podrobnosti
izdano v:Front Neurosci
Main Authors: Liu, Jun-Lin, Fan, Yong-Gang, Yang, Zheng-Sheng, Wang, Zhan-You, Guo, Chuang
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139360/
https://ncbi.nlm.nih.gov/pubmed/30250423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00632
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