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Iron and Alzheimer’s Disease: From Pathogenesis to Therapeutic Implications

As people age, iron deposits in different areas of the brain may impair normal cognitive function and behavior. Abnormal iron metabolism generates hydroxyl radicals through the Fenton reaction, triggers oxidative stress reactions, damages cell lipids, protein and DNA structure and function, and ulti...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Liu, Jun-Lin, Fan, Yong-Gang, Yang, Zheng-Sheng, Wang, Zhan-You, Guo, Chuang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139360/
https://ncbi.nlm.nih.gov/pubmed/30250423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00632
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