Comparative Glycopeptide Analysis for Protein Glycosylation by Liquid Chromatography and Tandem Mass Spectrometry: Variation in Glycosylation Patterns of Site-Directed Mutagenized Glycoprotein

Glycosylation is one of the most important posttranslational modifications for proteins, including therapeutic antibodies, and greatly influences protein physiochemical properties. In this study, glycopeptide mapping of a reference and biosimilar recombinant antibodies (rAbs) was performed using liq...

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Enregistré dans:
Détails bibliographiques
Publié dans:Int J Anal Chem
Auteurs principaux: Hahm, Young Hye, Hahm, Sung Ho, Jo, Hyoun Young, Ahn, Yeong Hee
Format: Artigo
Langue:Inglês
Publié: Hindawi 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139207/
https://ncbi.nlm.nih.gov/pubmed/30245723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/8605021
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