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Targeting USP7 identifies a metastasis-competent state within bone marrow-resident melanoma CTCs

Systemic metastasis is the major cause of death from melanoma, the most lethal form of skin cancer. Although most melanoma patients exhibit a substantial gap between onset of primary and metastatic tumors, signaling mechanisms implicated in the period of metastatic latency remain unclear. We hypothe...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Vishnoi, Monika, Boral, Debasish, Liu, Haowen, Sprouse, Marc L., Yin, Wei, Goswami-Sewell, Debalina, Tetzlaff, Michael T., Davies, Michael A., Glitza Oliva, Isabella C., Marchetti, Dario
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139068/
https://ncbi.nlm.nih.gov/pubmed/30026332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-0644
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