PMN-MDSCs Enhance CTC Metastatic Properties through Reciprocal Interactions via ROS/Notch/Nodal Signaling

Intratumoral infiltration of myeloid-derived suppressor cells (MDSCs) is known to promote neoplastic growth by inhibiting the tumoricidal activity of T cells. However, direct interactions between patient-derived MDSCs and circulating tumors cells (CTCs) within the microenvironment of blood remain un...

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Pubblicato in:Int J Mol Sci
Autori principali: Sprouse, Marc L., Welte, Thomas, Boral, Debasish, Liu, Haowen N., Yin, Wei, Vishnoi, Monika, Goswami-Sewell, Debalina, Li, Lili, Pei, Guangsheng, Jia, Peilin, Glitza-Oliva, Isabella C., Marchetti, Dario
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514876/
https://ncbi.nlm.nih.gov/pubmed/31003475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20081916
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