Assessment of the Validity of Nuclear-Localized Androgen Receptor Splice Variant 7 in Circulating Tumor Cells as a Predictive Biomarker for Castration-Resistant Prostate Cancer

IMPORTANCE: A blood test to determine whether to treat patients with metastatic castration-resistant prostate cancer (mCRPC) with an androgen receptor signaling (ARS) inhibitor or taxane is an unmet medical need. OBJECTIVE: To determine whether a validated assay for the nuclear-localized androgen re...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JAMA Oncol
Prif Awduron: Scher, Howard I., Graf, Ryon P., Schreiber, Nicole A., Jayaram, Anuradha, Winquist, Eric, McLaughlin, Brigit, Lu, David, Fleisher, Martin, Orr, Sarah, Lowes, Lori, Anderson, Amanda, Wang, Yipeng, Dittamore, Ryan, Allan, Alison L., Attard, Gerhardt, Heller, Glenn
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Medical Association 2018
Pynciau:
Original Investigation
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139066/
https://ncbi.nlm.nih.gov/pubmed/29955787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2018.1621
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