Assessment of the Validity of Nuclear-Localized Androgen Receptor Splice Variant 7 in Circulating Tumor Cells as a Predictive Biomarker for Castration-Resistant Prostate Cancer

IMPORTANCE: A blood test to determine whether to treat patients with metastatic castration-resistant prostate cancer (mCRPC) with an androgen receptor signaling (ARS) inhibitor or taxane is an unmet medical need. OBJECTIVE: To determine whether a validated assay for the nuclear-localized androgen re...

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Dades bibliogràfiques
Publicat a:JAMA Oncol
Autors principals: Scher, Howard I., Graf, Ryon P., Schreiber, Nicole A., Jayaram, Anuradha, Winquist, Eric, McLaughlin, Brigit, Lu, David, Fleisher, Martin, Orr, Sarah, Lowes, Lori, Anderson, Amanda, Wang, Yipeng, Dittamore, Ryan, Allan, Alison L., Attard, Gerhardt, Heller, Glenn
Format: Artigo
Idioma:Inglês
Publicat: American Medical Association 2018
Matèries:
Original Investigation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139066/
https://ncbi.nlm.nih.gov/pubmed/29955787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2018.1621
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