Assessment of the Validity of Nuclear-Localized Androgen Receptor Splice Variant 7 in Circulating Tumor Cells as a Predictive Biomarker for Castration-Resistant Prostate Cancer

IMPORTANCE: A blood test to determine whether to treat patients with metastatic castration-resistant prostate cancer (mCRPC) with an androgen receptor signaling (ARS) inhibitor or taxane is an unmet medical need. OBJECTIVE: To determine whether a validated assay for the nuclear-localized androgen re...

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Detalhes bibliográficos
Publicado no:JAMA Oncol
Main Authors: Scher, Howard I., Graf, Ryon P., Schreiber, Nicole A., Jayaram, Anuradha, Winquist, Eric, McLaughlin, Brigit, Lu, David, Fleisher, Martin, Orr, Sarah, Lowes, Lori, Anderson, Amanda, Wang, Yipeng, Dittamore, Ryan, Allan, Alison L., Attard, Gerhardt, Heller, Glenn
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2018
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139066/
https://ncbi.nlm.nih.gov/pubmed/29955787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2018.1621
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