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Mitotic Exit dysfunction through the deregulation of APC/C characterizes cisplatin resistant state in epithelial ovarian cancer

PURPOSE: Acquired resistance to cisplatin is a major barrier to success in treatment of various cancers and understanding mitotic mechanisms unique to cisplatin resistant cancer cells can provide the basis for developing novel mitotic targeted therapies aimed at eradicating these cells. EXPERIMENTAL...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Nagaraj, Anil Belur, Kovalenko, Olga, Avelar, Rita, Joseph, Peronne, Brown, Annalyn, Surti, Arshia, Mantilla, Sandra, DiFeo, Analisa
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139058/
https://ncbi.nlm.nih.gov/pubmed/29653924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-2885
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