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Mitotic Exit dysfunction through the deregulation of APC/C characterizes cisplatin resistant state in epithelial ovarian cancer

PURPOSE: Acquired resistance to cisplatin is a major barrier to success in treatment of various cancers and understanding mitotic mechanisms unique to cisplatin resistant cancer cells can provide the basis for developing novel mitotic targeted therapies aimed at eradicating these cells. EXPERIMENTAL...

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Dettagli Bibliografici
Pubblicato in:Clin Cancer Res
Autori principali: Nagaraj, Anil Belur, Kovalenko, Olga, Avelar, Rita, Joseph, Peronne, Brown, Annalyn, Surti, Arshia, Mantilla, Sandra, DiFeo, Analisa
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139058/
https://ncbi.nlm.nih.gov/pubmed/29653924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-2885
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