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Viable spores of Coccidioides posadasii Δcps1 are required for vaccination and provide long lasting immunity
Coccidioidomycosis is a systemic fungal infection for which a vaccine has been sought for over fifty years. The avirulent Coccidioides posadasii strain, Δcps1, which is missing a 6 kb gene, showed significant protection in mice. These studies explore conditions of protection in mice and elucidate th...
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| Publié dans: | Vaccine |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6139032/ https://ncbi.nlm.nih.gov/pubmed/29724507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2018.04.026 |
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