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Viable spores of Coccidioides posadasii Δcps1 are required for vaccination and provide long lasting immunity

Coccidioidomycosis is a systemic fungal infection for which a vaccine has been sought for over fifty years. The avirulent Coccidioides posadasii strain, Δcps1, which is missing a 6 kb gene, showed significant protection in mice. These studies explore conditions of protection in mice and elucidate th...

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Bibliografiske detaljer
Udgivet i:Vaccine
Main Authors: Shubitz, Lisa F., Powell, Daniel A., Trinh, Hien T., Lewis, M. Lourdes, Orbach, Marc J., Frelinger, Jeffrey A., Galgiani, John N.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139032/
https://ncbi.nlm.nih.gov/pubmed/29724507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2018.04.026
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