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Sirtuin 3-dependent mitochondrial redox homeostasis protects against AGEs-induced intervertebral disc degeneration

Intervertebral disc (IVD) degeneration contributes largely to pathoanatomical and degenerative changes of spinal structure that increase the risk of low back pain. Apoptosis in nucleus pulposus (NP) can aggravate IVD degeneration, and increasing studies have shown that interventions targeting NP cel...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Song, Yu, Li, Shuai, Geng, Wen, Luo, Rongjin, Liu, Wei, Tu, Ji, Wang, Kun, Kang, Liang, Yin, Huipeng, Wu, Xinghuo, Gao, Yong, Zhang, Yukun, Yang, Cao
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139007/
https://ncbi.nlm.nih.gov/pubmed/30216853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.09.006
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