Sirtuin 3-dependent mitochondrial redox homeostasis protects against AGEs-induced intervertebral disc degeneration

Intervertebral disc (IVD) degeneration contributes largely to pathoanatomical and degenerative changes of spinal structure that increase the risk of low back pain. Apoptosis in nucleus pulposus (NP) can aggravate IVD degeneration, and increasing studies have shown that interventions targeting NP cel...

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Dettagli Bibliografici
Pubblicato in:Redox Biol
Autori principali: Song, Yu, Li, Shuai, Geng, Wen, Luo, Rongjin, Liu, Wei, Tu, Ji, Wang, Kun, Kang, Liang, Yin, Huipeng, Wu, Xinghuo, Gao, Yong, Zhang, Yukun, Yang, Cao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139007/
https://ncbi.nlm.nih.gov/pubmed/30216853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.09.006
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