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Alternative splicing links histone modifications to stem cell fate decision

BACKGROUND: Understanding the embryonic stem cell (ESC) fate decision between self-renewal and proper differentiation is important for developmental biology and regenerative medicine. Attention has focused on mechanisms involving histone modifications, alternative pre-messenger RNA splicing, and cel...

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Publié dans:Genome Biol
Auteurs principaux: Xu, Yungang, Zhao, Weiling, Olson, Scott D., Prabhakara, Karthik S., Zhou, Xiaobo
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138936/
https://ncbi.nlm.nih.gov/pubmed/30217220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1512-3
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