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Skeletal Muscle Dystrophy mutant of lamin A alters the structure and dynamics of the Ig fold domain

Mutations in the different domains of A-type lamin proteins cause a diverse plethora of diseases collectively termed as laminopathies which can affect multiple organs. Ig fold is one such domain of lamin A which is implicated in numerous nuclear interactions wherein the mutations lead to different l...

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Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Dutta, Subarna, Das, Jitendra K., Maganti, Lakshmi, Bhattacharyya, Maitree, Bhattacharyya, Dhananjay, Mukherjee, Sujoy, Sengupta, Kaushik
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138676/
https://ncbi.nlm.nih.gov/pubmed/30218058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32227-2
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