The highly conserved nuclear lamin Ig-fold binds to PCNA: its role in DNA replication

This study provides insights into the role of nuclear lamins in DNA replication. Our data demonstrate that the Ig-fold motif located in the lamin C terminus binds directly to proliferating cell nuclear antigen (PCNA), the processivity factor necessary for the chain elongation phase of DNA replicatio...

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Main Authors: Shumaker, Dale K., Solimando, Liliana, Sengupta, Kaushik, Shimi, Takeshi, Adam, Stephen A., Grunwald, Antje, Strelkov, Sergei V., Aebi, Ueli, Cardoso, M. Cristina, Goldman, Robert D.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2008
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2315674/
https://ncbi.nlm.nih.gov/pubmed/18426975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200708155
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