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Developing TRAIL/TRAIL-death receptor-based cancer therapies
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily that can initiate the apoptosis pathway by binding to its associated death receptors DR4 and DR5. The activation of the TRAIL pathway in inducing tumor-selective apoptosis leads to the developmen...
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| Udgivet i: | Cancer Metastasis Rev |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6138568/ https://ncbi.nlm.nih.gov/pubmed/29541897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-018-9728-y |
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