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ONC201 activates ER stress to inhibit the growth of triple-negative breast cancer cells
ONC201 was previously identified as a first-in-class antitumor agent and small-molecule inducer of the TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) gene that induces apoptosis in cancer cells. ONC201 has a safety profile and is currently in phase II clinical trials for the treatme...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5400611/ https://ncbi.nlm.nih.gov/pubmed/28423492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15451 |
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