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Developing TRAIL/TRAIL-death receptor-based cancer therapies

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily that can initiate the apoptosis pathway by binding to its associated death receptors DR4 and DR5. The activation of the TRAIL pathway in inducing tumor-selective apoptosis leads to the developmen...

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Detalhes bibliográficos
Publicado no:Cancer Metastasis Rev
Main Authors: Yuan, Xun, Gajan, Ambikai, Chu, Qian, Xiong, Hua, Wu, Kongming, Wu, Gen Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138568/
https://ncbi.nlm.nih.gov/pubmed/29541897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-018-9728-y
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