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Structure–Activity Relationships (SARs) of the Competence Stimulating Peptide (CSP) in Streptococcus mutans Reveal Motifs Critical for Membrane Protease SepM Recognition and ComD Receptor Activation

Streptococcus mutans is a Gram-positive human pathogen that is one of the major contributors to dental caries, a condition with an economic cost of over $100 billion per year in the United States. S. mutans secretes a 21-amino-acid peptide termed the competence stimulating peptide (21-CSP) to assess...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Bikash, Chowdhury Raihan, Hamry, Sally R., Tal-Gan, Yftah
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138527/
https://ncbi.nlm.nih.gov/pubmed/29990430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.8b00115
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