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Identification of Highly Potent Competence Stimulating Peptide-Based Quorum Sensing Activators in Streptococcus mutans Through the Utilization of N-Methyl and Reverse Alanine Scanning
Quorum sensing (QS) controls the pathogenic behavior of Streptococcus mutans, a primary cause of dental caries. S. mutans uses the competence stimulating peptide (CSP) to control mutacin production, a bacteriocin utilized by S. mutans to outcompete different commensal bacteria in mixed biofilm envir...
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| Publicat a: | Bioorg Med Chem Lett |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6379129/ https://ncbi.nlm.nih.gov/pubmed/30711392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2019.01.029 |
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