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Identification of Highly Potent Competence Stimulating Peptide-Based Quorum Sensing Activators in Streptococcus mutans Through the Utilization of N-Methyl and Reverse Alanine Scanning

Quorum sensing (QS) controls the pathogenic behavior of Streptococcus mutans, a primary cause of dental caries. S. mutans uses the competence stimulating peptide (CSP) to control mutacin production, a bacteriocin utilized by S. mutans to outcompete different commensal bacteria in mixed biofilm envir...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Bikash, Chowdhury Raihan, Tal-Gan, Yftah
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6379129/
https://ncbi.nlm.nih.gov/pubmed/30711392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2019.01.029
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