Structure–Activity Relationships of the Competence Stimulating Peptides (CSPs) in Streptococcus pneumoniae Reveal Motifs Critical for intra-group and cross-group ComD Receptor Activation

Streptococcus pneumoniae is a highly recombinogenic human pathogen that utilizes the competence stimulating peptide (CSP)-based quorum sensing (QS) circuitry to acquire antibiotic resistance genes from the environment and initiate its attack on the human host. Modulation of QS in this bacterium, eit...

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Publicado en:ACS Chem Biol
Main Authors: Yang, Yifang, Koirala, Bimal, Sanchez, Lucia A., Phillips, Naiya R., Hamry, Sally R., Tal-Gan, Yftah
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400695/
https://ncbi.nlm.nih.gov/pubmed/28221753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00007
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