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Structural Characterization of Competence Stimulating Peptides (CSPs) Analogues Reveals Key Features for ComD1 and ComD2 Receptor Binding in Streptococcus pneumoniae

Streptococcus pneumoniae is an important pathogen that utilizes quorum sensing (QS) to regulate genetic transformation, virulence and biofilm formation. The competence stimulating peptide (CSP) is a 17-amino acid signal peptide that is used by S. pneumoniae to trigger QS. S. pneumoniae strains can b...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biochemistry
Hauptverfasser: Yang, Yifang, Cornilescu, Gabriel, Tal-Gan, Yftah
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6145841/
https://ncbi.nlm.nih.gov/pubmed/30125091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00653
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