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A comparative pharmacokinetic study of DRL_BZ, a candidate biosimilar of bevacizumab, with Avastin(®) (EU and US) in healthy male subjects
AIM: The aim of this study was to compare the pharmacokinetics (PK) of DRL_BZ with that of EU‐approved (reference medicinal product; RMP) and US‐licensed (reference product; RP) bevacizumab (Avastin(®)) in healthy male subjects. METHODS: In this double‐blind, parallel‐group, Phase 1 study (BZ‐01‐001...
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| Publicado no: | Br J Clin Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6138499/ https://ncbi.nlm.nih.gov/pubmed/29943831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13691 |
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