Pharmacokinetics of intravitreal bevacizumab (Avastin(®)) in rabbits

PURPOSE: To describe the pharmacokinetics of intravitreal bevacizumab (Avastin(®)) in rabbits. METHODS: The right eye of 20 rabbits was injected intravitreally with 1.25 mg/0.05 mL bevacizumab. Both eyes of four rabbits each time were enucleated at days 1, 3, 8, 15, and 29. Bevacizumab concentration...

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Detalhes bibliográficos
Main Authors: Sinapis, Christos I, Routsias, John G, Sinapis, Angelos I, Sinapis, Dimitrios I, Agrogiannis, George D, Pantopoulou, Alkistis, Theocharis, Stamatis E, Baltatzis, Stefanos, Patsouris, Efstratios, Perrea, Despoina
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2011
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104800/
https://ncbi.nlm.nih.gov/pubmed/21629577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OPTH.S19555
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