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A comparative pharmacokinetic study of DRL_BZ, a candidate biosimilar of bevacizumab, with Avastin(®) (EU and US) in healthy male subjects

AIM: The aim of this study was to compare the pharmacokinetics (PK) of DRL_BZ with that of EU‐approved (reference medicinal product; RMP) and US‐licensed (reference product; RP) bevacizumab (Avastin(®)) in healthy male subjects. METHODS: In this double‐blind, parallel‐group, Phase 1 study (BZ‐01‐001...

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Detalles Bibliográficos
Publicado en:Br J Clin Pharmacol
Main Authors: Wynne, Chris, Schwabe, Christian, Batra, Sonica Sachdeva, Lopez‐Lazaro, Luis, Kankanwadi, Suresh
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138499/
https://ncbi.nlm.nih.gov/pubmed/29943831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13691
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