Zika virus elicits inflammation to evade antiviral response by cleaving cGAS via NS1‐caspase‐1 axis

Viral infection triggers host innate immune responses, which primarily include the activation of type I interferon (IFN) signaling and inflammasomes. Here, we report that Zika virus (ZIKV) infection triggers NLRP3 inflammasome activation, which is further enhanced by viral non‐structural protein NS1...

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Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Zheng, Yanyan, Liu, Qingxiang, Wu, Yaoxing, Ma, Ling, Zhang, Zhenzhen, Liu, Tao, Jin, Shouheng, She, Yuanchu, Li, Yi‐Ping, Cui, Jun
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138430/
https://ncbi.nlm.nih.gov/pubmed/30065070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899347
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